Tacrolimus-Induced Gingival Enlargement: A Case Report
نویسنده
چکیده
Gingival enlargement poses functional as well as cosmetic problems. It affects the quality of life by interfering with mastication, speech, occlusion and maintaining optimal oral hygiene .Gingival enlargement induced by cyclosporine A has been well documented in the literature. Only few studies, however, have associated the occurrence of such condition with the use of tacrolimus. A case of 48 years old female patient presented with a generalized gingival enlargement is reported. A medical history revealed a hepatic transplantation and a current immunosuppressive therapy based on tacrolimus. In this case report, surgical excision of the enlarged gingival tissues was presented. The findings of the present case suggest that tacrolimus immunosuppressive therapy may induce gingival enlargement in some patients. Hence, obtaining a thorough medical history is critical to reach a definite diagnosis. [A.S. Alzahrani and N.K. Awad. Tacrolimus-Induced Gingival Enlargement: A Case Report. J Am Sci 2013;9 (4):271-274]. (ISSN: 1545-1003). http://www.americanscience.org. 37
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